个人简历:
1985年毕业于四川大学生物系遗传专业,获学士学位;1988年毕业于北京农业大学作物遗传育种专业,获硕士学位;1991年受美国洛克菲勒基金会资助留学英国,1996年毕业于英国Nottingham大学生命科学系植物生物技术专业,获博士学位。1996-2003年在复旦大学遗传工程国家重点实验室工作,先后任副教授、教授、博士生导师、植物遗传工程组组长。其间,于1997、1998和1999年获得美国洛克菲勒基金会职业奖学金到英国John Innes研究中心和美国加州大学Davis分校开展植物生物技术领域合作研究,2003年调入上海交通大学工作。曾任上海交通大学农业与生物学院院长、国家863“十五”计划生物工程技术主题专家和生物反应器重大专项专家、5个国家重点实验室(遗传工程、植物分子遗传、作物遗传改良、热带作物生物技术、水稻生物学)和国家转基因植物及产业化基地等学术委员会委员及SCI期刊<<Molecular Plant >>编委。
现任上海交通大学植物生物技术研究中心主任、复旦-交大-诺丁汉植物生物技术研发中心主任、农业与生物学院教授。上海市优秀学科带头人、上海市领军人才、国家政府特殊津贴获得者、瑞典林奈大学名誉博士。兼任中国植物生理学会常务理事、上海市植物生理学会副理事长、上海市生物工程学会副理事长、上海市第十一届、第十二届政协委员。担任SCI期刊<<Plant Cell, Tissue and Organ Culture>>和<<Biotechnology and Applied Biochemistry>>副主编、<<Frontiers in Plant Science>>和<<BioMed Research International>>编委,核心期刊<<Frontiers of Agricultural Science and Engineering >>、<<农业生物技术学报>>、<<植物学报>>、<<应用与环境生物学报>>和<<中国生物工程杂志>>等编委。
研究方向
(1)植物代谢调控与代谢工程
(2)植物生物反应器
(3)植物分子生物学
研究项目:
1)农作物特殊营养品质的代谢工程(国家973计划项目2007CB108805,2007年-2011年,565万元)
2)抗蚜虫转基因小麦新品系和新种质创制(国家转基因重大专项2008ZX08002-001,2011ZX08002-001,2008年-2012年,590万元)
3)抗蚜虫转基因小麦新品系培(国家转基因重大专项2016ZX08002001-006,2016年-2020年,500万元)
4)青蒿药物植物产品关键技术研究与应用(上海市科委重点项目08391911800,2008年-2011年,100万元)
5)植物代谢产物生物反应器产品研发(国家863计划重大项目2011AA100605,2011年-2016年,861万元)
成果专利与奖励:
申请或授权中国国家发明专利160余项,其中授权发明专利50余项。以第一完成人获得2009年高等教育上海市级教学成果二等奖和2014年上海市技术发明二等奖。
论文论著:
在SCI期刊上发表论文300余篇, 编辑书籍3部:《植物生物技术》(张献龙、唐克轩主编,科学出版社,2004)、《中草药生物技术》(唐克轩主编,复旦大学出版社,2005)、《细胞工程》(陈志南主编、唐克轩副主编,科学出版社,2005)。
代表性论文如下:
- Yan, T., Chen, M., Shen, Q., Li, L., Fu, X., Pan, Q., Tang, Y., Shi, P., Lv, Z., Jiang, W., Ma, Y., Hao, X., Sun, X. and Tang, K. (2016). Promotion of glandular trichome initiation by a homeodomain transcription factor AaHD1 in Artemisia annua. New Phytologist (in press).
- Lv, Z., Wang, S., Zhang, F., Chen, L., Pan, Q., Hao, X., Fu, X., Li, L., Sun, X. and Tang, K. (2016). Overexpression of a novel NAC domain-containing transcription factor (AaNAC1) enhances the content of artemisinin and increases tolerance to drought and Botrytis cinerea in Artemisia annua. Plant and Cell Physiology (in press)
- Tang, K., Shen, Q., Lu X. and Zhang, F. (2016). Improving artemisinin content in Artemisia annua by transcription factor regulation. Science (supplement): 48-51.
- Shen, Q., Lu, X., Yan, T., Fu, X., Lv, Z., Zhang, F., Pan, Q., Wang, G., Sun, X. and Tang, K. (2016). The jasmonate-responsive AaMYC2 transcription factor positively regulates artemisinin biosynthesis in Artemisia annua. New Phytologist 210: 1269-1281.
- Lv, Z., Zhang, F., Pan, Q., Fu, X., Jiang, W., Shen, Q., Yan, T., Shi, P., Lu, X., Sun, X. and Tang, K. (2016). Branch Pathway Blocking in Artemisia annua is a Useful Method for Obtaining High Yield Artemisinin. Plant and Cell Physiology 57(3): 588-602.
- Moses, T., Pollier, J., Shen, Q., Soetaert, S., Reed, J., Erffelinck, M., Van Nieuwerburgh, F.C.W., Bossche, R.V., Osbourn, A., Thevelein, J.M., Deforce, D., Tang, K. and Goossens, A. (2015). OSC2 and CYP716A14v2 Catalyze the Biosynthesis of Triterpenoids for the Cuticle of Aerial Organs of Artemisia annua. Plant Cell. 27(1), 286-301
- Zhang, F., Fu, X., Lv, Z., Lu, X., Shen, Q., Zhang, L., Zhu, M., Wang, G., Sun, X., Liao, Z. and Tang K. (2015). AabZIP1, Connects Abscisic Acid Signaling with Artemisinin Biosynthesis in Artemisia annua. Molecular Plant 8: 163-175.
- Lu X, Zhang F, Shen Q, Jiang W, Pan Q, Lv Z, Yan, T., Fu, X., Wang, Y., Qian, H. and Tang, K. (2014) Overexpression of Allene Oxide Cyclase Improves the Biosynthesis of Artemisinin in Artemisia annua L.. PLoS ONE 9(3): e91741.
- Lu, X., Zhang, L., Zhang, F., Jiang, W., Shen, Q., Zhang, L., Lv, Z., Wang, G. and Tang, K. (2013). AaORA, a trichome-specific AP2/ERF transcription factor of Artemisia annua, is a positive regulator in the artemisinin biosynthetic pathway and in disease resistance to Botrytis cinerea. New Phytologist 198: 1191-1202.
- Lu, X., Jiang, W., Zhang, L., Zhang, F., Zhang, F., Shen, Q., Wang, G. and Tang, K. (2013). AaERF1 positively regulates the resistance to B. cinerea in Artemisia annua. PLoS ONE 8(2): e57657.
- Zhang, F., Lu, X., Lv, Z., Zhang, L., Zhu, M., Jiang, W., Wang, G., Sun, X. and Tang. K (2013). Overexpression of the Artemisia orthologue of ABA receptor, AaPYL9, enhances ABA sensitivity and improves artemisinin content in Artemisia annua L. PLoS ONE 8(2): e56697
- Pan, Q., Wang, Q., Yuan, F., Xing, S., Zhao, J., Choi, Y., Verpoorte, R., Tian, Y., Wang, G. and Tang, K. (2012). Overexpression of ORCA3 and G10H in Catharanthus roseus plants regulated alkaloid biosynthesis and metabolism revealed by NMR-metabolomics. PLoS ONE 7(8): e43038.
- Zhang, F., Zuo, K., Zhang, J., Liu, X., Zhang, L., Sun, X. and Tang, K. (2010). An L1 box binding protein, GbML1, interacts with GbMYB25 to control cotton fibre development. Journal of Experimental Botany 61(13):3599–3613.
- Liu, X., Zuo, K., Xu, J., Li, Y., Zhang, F., Yao, H., Wang, Y., Chen, Y., Qiu, C., Sun, X. and Tang K. (2010). Functional analysis of GbAGL1, a D-lineage gene from cotton (Gossypium barbadense). Journal of Experimental Botany 61(4): 1193-1203
- Zhang, L., Li, Y., Wang, Z., Xia, Y., Chen, W. and Tang, K. (2007). Recent Developments and Future Prospects of Vitreoscilla Hemoglobin Application in Metabolic Engineering. Biotechnology Advances 25: 123-136.
- Zhang, L., Wang, Z., Xia, Y., Kai, G., Chen, W. and Tang, K. (2007). Metabolic Engineering of Plant L-ascorbic Acid Biosynthesis: Recent Trends and Applications. Critical Reviews in Biotechnology 27(3):173-182.
- Zhang, L., Ding, R., Chai, Y., Bonfill, M., Moyano, E., Oksman-Caldentey, K-M., Xu, T., Pi, Y., Wang, Z., Zhang, H., Kai, G., Liao, Z., Sun, X., and Tang, K. (2004). Engineering tropane biosynthetic pathway in Hyoscyamus niger hairy root cultures. Proceedings of the National Academy of Sciences USA 101(17): 6786-6791.
- Zhang, L., Yuan, D., Yu, S., Li, Z., Cao, Y., Miao, Z., Qian, H. and Tang, K. (2004). Preference of simple sequence repeats in coding and non-coding regions of Arabidopsis thaliana. Bioinformatics 20(7): 1081-1086.
- Yao, J., Zhao, X., Liao, Z., Lin, J., Chen, Z., Chen, F., Song, J., Sun, X. and Tang, K. (2003). Cloning and molecular characterization of a novel lectin gene from Pinellia ternata. Cell Research 13(4): 301-308.